048-441-0493
〒335-0002 埼玉県蕨市塚越1-5-7 蕨駅より徒歩2分

動物と人に優しい女性獣医師と、もしもの時の専門医

診療案内

ホーム>診療案内

  • 一般診療
  • 腫瘍科専門外来/がんのセカンドオピニオン外来
  • 電気化学療法

参考文献とエビデンス

  • 電気化学療法に関連した論文(犬)
  • 電気化学療法に関連した論文(猫)

肥満細胞腫

The treatment of canine mast cell tumours with electrochemotherapy with or without surgical excision.
Lowe R, Gavazza A, Impellizeri JA, Soden DM, Lubas G.
Vet Comp Oncol. 2017 Sep;15(3):775-784. doi: 10.1111/vco.12217. Epub 2016 Mar 22.
Numerical model of dog mast cell tumor treated by electrochemotherapy.
Suzuki DO, Anselmo J, de Oliveira KD, Freytag JO, Rangel MM, Marques JL, Ramos A.
Artif Organs. 2015 Feb;39(2):192-7. doi: 10.1111/aor.12333. Epub 2014 Jul 9.
Evaluation of Cisplatin as an electrochemotherapy agent for the treatment of incompletely excised mast cell tumors in dogs.
Spugnini EP, Vincenzi B, Citro G, Dotsinsky I, Mudrov T, Baldi A.
J Vet Intern Med. 2011 Mar-Apr;25(2):407-11. doi: 10.1111/j.1939-1676.2011.0678.x. Epub 2011 Feb 11.
Electrochemotherapy compared to surgery for treatment of canine mast cell tumours.
Kodre V, Cemazar M, Pecar J, Sersa G, Cor A, Tozon N.
In Vivo. 2009 Jan-Feb;23(1):55-62.
Adjuvant electrochemotherapy for the treatment of incompletely resected canine mast cell tumors.
Spugnini EP, Vincenzi B, Baldi F, Citro G, Baldi A.
Anticancer Res. 2006 Nov-Dec;26(6B):4585-9.

軟部組織肉腫

Surgery and electrochemotherapy of a high-grade soft tissue sarcoma in a dog.
Spugnini EP, Vincenzi B, Betti G, Cordahi F, Dotsinsky I, Mudrov N, Citro G, Baldi A.
Vet Rec. 2008 Feb 9;162(6):186-8. No abstract available.
Adjuvant electrochemotherapy for the treatment of incompletely excised spontaneous canine sarcomas.
Spugnini EP, Vincenzi B, Citro G, Santini D, Dotsinsky I, Mudrov N, Montesarchio V, Laieta MT, Esposito V, Baldi A.
In Vivo. 2007 Sep-Oct;21(5):819-22

鼻腔内腫瘍

Minimally Invasive Electrochemotherapy Procedure for Treating Nasal Duct Tumors in Dogs using a Single Needle Electrode.
Maglietti F, Tellado M, Olaiz N, Michinski S, Marshall G.
Radiol Oncol. 2017 Nov 1;51(4):422-430. doi: 10.1515/raon-2017-0043. eCollection 2017 Dec.

肛門嚢アポクリン腺癌 / 肛門周囲腺腫 / 肛門周囲腺癌 / 他

Successful rescue of an apocrine gland carcinoma metastatic to the cervical lymph nodes by mitoxantrone coupled with trains of permeabilizing electrical pulses (electrochemotherapy).
Spugnini EP, Dotsinsky I, Mudrov N, De Luca A, Codini C, Citro G, D'Avino A, Baldi A.
In Vivo. 2008 Jan-Feb;22(1):51-3
Adjuvant electrochemotherapy for incompletely excised anal sac carcinoma in a dog.
Spugnini EP, Dotsinsky I, Mudrov N, Bufalini M, Giannini G, Citro G, Feroce F, Baldi A.
In Vivo. 2008 Jan-Feb;22(1):47-9.
Biphasic pulses enhance bleomycin efficacy in a spontaneous canine perianal tumors model.
Spugnini EP, Dotsinsky I, Mudrov N, Cardosi G, Citro G, D'Avino A, Baldi A.
J Exp Clin Cancer Res. 2007 Dec;26(4):483-7.
Local control and distant metastasis after electrochemotherapy of a canine anal melanoma.
Spugnini EP, Filipponi M, Romani L, Dotsinsky I, Mudrov N, Baroni A, Ruocco E, Laieta MT, Montesarchio V, Cassandro R, Citro G, Baldi A.
In Vivo. 2007 Sep-Oct;21(5):897-9.
Effective treatment of perianal tumors in dogs with electrochemotherapy.
Tozon N, Kodre V, Sersa G, Cemazar M.
Anticancer Res. 2005 Mar-Apr;25(2A):839-45.

レビュー他

Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats.
Tozon N, Lampreht Tratar U, Znidar K, Sersa G, Teissie J, Cemazar M.
J Vis Exp. 2016 Oct 24;(116). doi: 10.3791/54760.
Electrochemotherapy as First Line Cancer Treatment: Experiences from Veterinary Medicine in Developing Novel Protocols.
Spugnini EP, Azzarito T, Fais S, Fanciulli M, Baldi A.
Curr Cancer Drug Targets. 2016;16(1):43-52. Review.
Electrochemotherapy for the treatment of recurring aponeurotic fibromatosis in a dog.
Spugnini EP, Di Tosto G, Salemme S, Pecchia L, Fanciulli M, Baldi A.
Can Vet J. 2013 Jun;54(6):606-9.
Preclinical models in electrochemotherapy: the role of veterinary patients.
Spugnini EP, Fanciulli M, Citro G, Baldi A.
Future Oncol. 2012 Jul;8(7):829-37. doi: 10.2217/fon.12.64. Review.
Electrochemotherapy in veterinary oncology.
Cemazar M, Tamzali Y, Sersa G, Tozon N, Mir LM, Miklavcic D, Lowe R, Teissie J.
J Vet Intern Med. 2008 Jul-Aug;22(4):826-31. doi: 10.1111/j.1939-1676.2008.0117.x. Review.
Electrochemotherapy for localized lymphoma: a preliminary study in companion animals.
Spugnini EP, Citro G, Mellone P, Dotsinsky I, Mudrov N, Baldi A.
J Exp Clin Cancer Res. 2007 Sep;26(3):343-6.
Patterns of tumor response in canine and feline cancer patients treated with electrochemotherapy: preclinical data for the standardization of this treatment in pets and humans.
Spugnini EP, Baldi F, Mellone P, Feroce F, D'Avino A, Bonetto F, Vincenzi B, Citro G, Baldi A.
J Transl Med. 2007 Oct 2;5:48.
Potentiation of chemotherapy in companion animals with spontaneous large neoplasms by application of biphasic electric pulses.
Spugnini EP, Porrello A.
J Exp Clin Cancer Res. 2003 Dec;22(4):571-80.
Electrochemotherapy: potentiation of local antitumour effectiveness of cisplatin in dogs and cats.
Tozon N, Sersa G, Cemazar M.
Anticancer Res. 2001 Jul-Aug;21(4A):2483-8.

扁平上皮癌

Electroporation Enhances Bleomycin Efficacy in Cats with Periocular Carcinoma and Advanced Squamous Cell Carcinoma of the Head.
Spugnini EP, Pizzuto M, Filipponi M, Romani L, Vincenzi B, Menicagli F, Lanza A, De Girolamo R, Lomonaco R, Fanciulli M, Spriano G, Baldi A.
J Vet Intern Med. 2015 Sep-Oct;29(5):1368-75. doi: 10.1111/jvim.13586. Epub 2015 Jul 20.
Electrochemotherapy with intravenous bleomycin injection: an observational study in superficial squamous cell carcinoma in cats.
Tozon N, Pavlin D, Sersa G, Dolinsek T, Cemazar M.
J Feline Med Surg. 2014 Apr;16(4):291-9. doi: 10.1177/1098612X13507071. Epub 2013 Oct 14.
Electrochemotherapy for the treatment of squamous cell carcinoma in cats: a preliminary report.
Spugnini EP, Vincenzi B, Citro G, Tonini G, Dotsinsky I, Mudrov N, Baldi A.
Vet J. 2009 Jan;179(1):117-20. Epub 2007 Sep 29.

線維肉腫 / 非上皮系悪性腫瘍

Electrochemotherapy with cisplatin enhances local control after surgical ablation of fibrosarcoma in cats: an approach to improve the therapeutic index of highly toxic chemotherapy drugs.
Spugnini EP, Renaud SM, Buglioni S, Carocci F, Dragonetti E, Murace R, Cardelli P, Vincenzi B, Baldi A, Citro G.
J Transl Med. 2011 Sep 14;9:152. doi: 10.1186/1479-5876-9-152.
Electrochemotherapy treatment for bilateral pleomorphic rhabdomyosarcoma in a cat.
Spugnini EP, Filipponi M, Romani L, Dotsinsky I, Mudrov N, Citro G, Baldi A.
J Small Anim Pract. 2010 Jun;51(6):330-2. doi: 10.1111/j.1748-5827.2010.00913.x. Epub 2010 May 10.
Ganglioneuroblastoma in a cat: a rare neoplasm treated with electrochemotherapy.
Spugnini EP, Citro G, Dotsinsky I, Mudrov N, Mellone P, Baldi A.
Vet J. 2008 Nov;178(2):291-3. Epub 2007 Oct 1.
Thoracic haemangiopericytoma in a cat.
Baldi A, Spugnini EP.
Vet Rec. 2006 Oct 28;159(18):598-600. No abstract available.
Intraoperative versus postoperative electrochemotherapy in high grade soft tissue sarcomas: a preliminary study in a spontaneous feline model.
Spugnini EP, Baldi A, Vincenzi B, Bongiorni F, Bellelli C, Citro G, Porrello A.
Cancer Chemother Pharmacol. 2007 Feb;59(3):375-81. Epub 2006 Jun 29.
First clinical trial of cat soft-tissue sarcomas treatment by electrochemotherapy.
Mir LM, Devauchelle P, Quintin-Colonna F, Delisle F, Doliger S, Fradelizi D, Belehradek J Jr, Orlowski S.
Br J Cancer. 1997;76(12):1617-22.

レビュー他

Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats.
Tozon N, Lampreht Tratar U, Znidar K, Sersa G, Teissie J, Cemazar M.
J Vis Exp. 2016 Oct 24;(116). doi: 10.3791/54760.
Electrochemotherapy as First Line Cancer Treatment: Experiences from Veterinary Medicine in Developing Novel Protocols.
Spugnini EP, Azzarito T, Fais S, Fanciulli M, Baldi A.
Curr Cancer Drug Targets. 2016;16(1):43-52. Review.
Preclinical models in electrochemotherapy: the role of veterinary patients.
Spugnini EP, Fanciulli M, Citro G, Baldi A.
Future Oncol. 2012 Jul;8(7):829-37. doi: 10.2217/fon.12.64. Review.
Electrochemotherapy in veterinary oncology.
Cemazar M, Tamzali Y, Sersa G, Tozon N, Mir LM, Miklavcic D, Lowe R, Teissie J.
J Vet Intern Med. 2008 Jul-Aug;22(4):826-31. doi: 10.1111/j.1939-1676.2008.0117.x. Review.
Electrochemotherapy-induced radiation recall in a cat.
Spugnini EP, Dotsinsky I, Mudrov N, Citro G, Caruso G, Cardelli P, Baldi A.
In Vivo. 2008 Nov-Dec;22(6):751-3.
Electrochemotherapy for localized lymphoma: a preliminary study in companion animals.
Spugnini EP, Citro G, Mellone P, Dotsinsky I, Mudrov N, Baldi A.
J Exp Clin Cancer Res. 2007 Sep;26(3):343-6.
Patterns of tumor response in canine and feline cancer patients treated with electrochemotherapy: preclinical data for the standardization of this treatment in pets and humans.
Spugnini EP, Baldi F, Mellone P, Feroce F, D'Avino A, Bonetto F, Vincenzi B, Citro G, Baldi A.
J Transl Med. 2007 Oct 2;5:48
Potentiation of chemotherapy in companion animals with spontaneous large neoplasms by application of biphasic electric pulses.
Spugnini EP, Porrello A.
J Exp Clin Cancer Res. 2003 Dec;22(4):571-80.
Electrochemotherapy: potentiation of local antitumour effectiveness of cisplatin in dogs and cats.
Tozon N, Sersa G, Cemazar M.
Anticancer Res. 2001 Jul-Aug;21(4A):2483-8.